Your annual panel
Heart health is about far more than a standard cholesterol panel. Our comprehensive lab assessment looks across all systems that can influence cardiovascular and metabolic health—from lipoproteins and inflammation to blood sugar, hormones, nutrients, thyroid function, and more.
Educational information only. Which tests are right for you is decided with your clinician.
6 tests
Go beyond LDL cholesterol to better understand the particles and processes involved in atherosclerosis and cardiovascular risk.
A standard lipid panel measures four key markers: total cholesterol, LDL ("bad") cholesterol, HDL ("good") cholesterol, and triglycerides. These values provide a foundational assessment of cardiovascular risk and metabolic health.
Included in your annual panel Link
Apolipoprotein A1 is the primary protein component of HDL ("good") cholesterol particles and plays a central role in reverse cholesterol transport, the process by which excess cholesterol is removed from artery walls and transported to the liver for excretion. Higher ApoA1 levels are associated with reduced cardiovascular risk.
Included in your annual panel Link
ApoB counts the actual number of particles that can enter your artery wall. Two people with the same LDL can have vastly different ApoB, and vastly different risk.
Included in your annual panel Link
Advanced lipid testing using ion mobility or NMR spectroscopy provides crucial information that standard cholesterol testing misses: it measures both the size and number of LDL particles. This distinction matters because not all LDL particles are equally dangerous.
Included in your annual panel Link
Lipoprotein(a), or Lp(a), is a genetically determined cardiovascular risk factor that affects approximately 20% of the population. It is essentially an LDL particle with an additional protein (apolipoprotein(a)) attached, making it particularly dangerous because it promotes both atherosclerosis and blood clotting.
Included in your annual panel Link
This panel measures key omega-3 (like EPA and DHA) and omega-6 fatty acids and the balance between them. That balance influences inflammation and cardiovascular health, and it’s one of the most responsive markers to dietary change, making it a useful way to track how nutrition shifts are landing.
Included in your annual panel Link
5 tests
Look for inflammatory and oxidative processes that may contribute to vascular injury and plaque development.
High-sensitivity C-Reactive Protein (hs-CRP) is the gold standard blood test for measuring systemic inflammation, a key driver of cardiovascular disease, metabolic dysfunction, and accelerated aging. Unlike standard CRP (used to detect acute infections), hs-CRP detects the low-grade chronic inflammation that silently damages blood vessels.
Included in your annual panel Link
Erythrocyte Sedimentation Rate measures how fast red blood cells settle. Elevated levels indicate inflammation.
Included in your annual panel Link
Myeloperoxidase is an enzyme released by active immune cells that points to inflammation within the blood-vessel wall itself, the kind tied to unstable, vulnerable plaque. It adds a vascular-specific layer to the inflammation picture that general markers can miss.
Included in your annual panel Link
Lp-PLA2 is an enzyme closely linked to inflammation inside the artery wall and to plaque that’s more prone to rupture. Unlike broad inflammatory markers, it’s relatively specific to vascular inflammation, helping distinguish arterial risk from general inflammation.
Included in your annual panel Link
Oxidized LDL reflects LDL particles that have been chemically damaged and are actively contributing to plaque formation and arterial inflammation. It’s one of the more direct signals of whether cholesterol is causing harm right now, rather than simply how much is circulating.
Included in your annual panel Link
4 tests
Understand how your body is regulating blood sugar, insulin, and other metabolic factors closely tied to cardiovascular risk.
Hemoglobin A1c (HbA1c) measures the percentage of hemoglobin proteins that have glucose attached to them, providing a picture of average blood sugar levels over the past 2-3 months. Unlike fasting glucose, which fluctuates daily, A1c captures long-term glycemic trends.
Included in your annual panel Link
Fasting insulin is one of the most important, yet most commonly overlooked, metabolic markers. It detects insulin resistance years or even decades before blood sugar becomes abnormal.
Included in your annual panel Link
The Comprehensive Metabolic Panel (CMP) is a foundational blood test that includes 14 markers covering glucose, electrolytes (sodium, potassium, chloride, bicarbonate), kidney function (BUN, creatinine), and liver health (AST, ALT, ALP, bilirubin, albumin, total protein). It provides a broad metabolic overview.
Included in your annual panel Link
Uric acid is a byproduct of purine metabolism that has traditionally been associated only with gout, but emerging research reveals it as a powerful marker and driver of metabolic dysfunction, cardiovascular disease, and kidney disease.
Included in your annual panel Link
2 tests
Assess biomarkers related to blood vessels, clotting, and cardiovascular risk.
Homocysteine is an amino acid produced during the methylation cycle, and elevated levels directly damage blood vessel walls, promote blood clots, and accelerate atherosclerosis. It is one of the most underappreciated cardiovascular risk factors.
Included in your annual panel Link
Fibrinogen is a clotting protein. Elevated levels increase clot risk and indicate chronic inflammation.
Included in your annual panel Link
5 tests
Evaluate thyroid function and autoimmunity, both of which can influence metabolism, cholesterol, energy, and cardiovascular health.
Thyroid Stimulating Hormone (TSH) is produced by the pituitary gland to stimulate the thyroid to produce T4 and T3 hormones. Paradoxically, higher TSH indicates that your thyroid is underperforming, the pituitary is "shouting louder" to get the thyroid to produce more hormones.
Included in your annual panel Link
Free T4 (thyroxine) is the main hormone produced by the thyroid gland and serves as the "storage" or "reservoir" form of thyroid hormone. It circulates in the blood and is converted into the active form, T3, by tissues throughout the body as needed.
Included in your annual panel Link
Free T3 (triiodothyronine) is the active thyroid hormone that actually enters cells and drives metabolic rate. While T4 is produced in much larger quantities by the thyroid, it must be converted to T3 to have biological effects.
Included in your annual panel Link
Thyroglobulin is the protein your thyroid stores its hormone in, and antibodies to it point at autoimmune activity from a different angle than TPO does. The two are reported separately because some people show one without the other, so measuring both gives a fuller view of what may sit behind a thyroid result.
Included in your annual panel Link
TPO antibodies target the enzyme your thyroid uses to build its hormones, and they are the antibody most often present when an autoimmune process is involved. Because thyroid status influences metabolism, cholesterol, and heart rate, knowing whether these antibodies are there adds context a TSH alone cannot give.
Included in your annual panel Link
1 test
Assess hormonal signals involved in the body's stress response.
Cortisol is the body’s primary stress hormone, and a morning measurement captures it near its natural daily peak. Chronically dysregulated cortisol is linked to blood pressure, metabolism, and cardiovascular risk, making it a meaningful part of a root-cause picture.
Included in your annual panel Link
6 tests
Female Hormone Health: Evaluate key sex hormones that influence metabolic, vascular, bone, and overall health.
Male Hormone Health: Evaluate key sex hormones that influence metabolic, cardiovascular, muscle, bone, and overall health.
In the female and male panels
Total testosterone includes both free and protein-bound forms. It indicates overall androgen status.
Included in your annual panel Link
In the female and male panels
Free testosterone is the active form not bound to proteins. It affects energy, mood, muscle, and libido.
Included in your annual panel Link
In the female and male panels
Estradiol is a primary form of estrogen relevant to people of all genders. It plays a role in blood-vessel function, bone, and metabolic health, so it’s part of the hormonal picture that shapes cardiovascular risk over time.
Included in your annual panel Link
In the female panel
Progesterone balances estrogen and supports mood, sleep, and reproductive health. Levels vary with menstrual cycle.
Included in your annual panel Link
In the female and male panels
DHEA-S is an adrenal hormone that declines with age. It's a precursor to both testosterone and estrogen.
Included in your annual panel Link
In the female and male panels
Sex Hormone Binding Globulin binds testosterone and estrogen. High SHBG reduces free hormone availability.
Included in your annual panel Link
7 tests
Identify nutrient levels and deficiencies that can influence cardiovascular health, energy, metabolism, and cellular function.
25-hydroxyvitamin D is the best measure of vitamin D status. Deficiency is common and associated with cardiovascular, immune, and metabolic health, and because it’s so responsive to supplementation and sunlight, it’s a highly actionable marker to track.
Included in your annual panel Link
Vitamin B12 (cobalamin) is essential for nerve function, DNA synthesis, red blood cell formation, and energy production.
Included in your annual panel Link
Folate is essential for DNA synthesis, methylation, and red blood cell production. Low levels increase homocysteine.
Included in your annual panel Link
Red blood cell magnesium is more accurate than serum magnesium. Magnesium is involved in 300+ enzymatic reactions.
Included in your annual panel Link
Zinc powers hundreds of enzymes involved in immune defense, tissue repair, taste and smell, and hormone production. Levels can run low with certain diets, medications, and gut conditions, and because deficiency is easy to correct once you can see it, it's a highly actionable marker.
Included in your annual panel Link
Serum iron reflects current iron status. It fluctuates with recent food intake and should be interpreted with ferritin and TIBC.
Included in your annual panel Link
Ferritin reflects iron stores. Both low and high levels are problematic, low causes fatigue, high indicates inflammation or iron overload.
Included in your annual panel Link
1 test
Evaluate red blood cells, white blood cells, platelets, oxygen-carrying capacity, and other fundamental markers of overall health.
A complete blood count measures red cells, white cells, and platelets. It screens for anemia, infection, and blood disorders.
Included in your annual panel Link
3 tests
Assess organs central to metabolism, digestion, detoxification, and blood sugar regulation.
Gamma-Glutamyl Transferase (GGT) is a liver enzyme that has emerged as a powerful predictor of metabolic dysfunction, cardiovascular disease, and all-cause mortality, far beyond its traditional role as a marker of liver disease and alcohol use.
Included in your annual panel Link
Amylase is a digestive enzyme from the pancreas and salivary glands. Elevated levels may indicate pancreatitis.
Included in your annual panel Link
Lipase is a pancreatic enzyme for fat digestion. More specific for pancreatic issues than amylase.
Included in your annual panel Link
2 tests
Screen for markers that may signal underlying autoimmune activity or systemic inflammation.
ANA is a screening marker for autoimmune activity. Because autoimmune and inflammatory conditions can quietly contribute to cardiovascular and whole-body risk, we include it to help surface immune drivers that standard cardiac workups overlook.
Included in your annual panel Link
Rheumatoid factor is an antibody linked to rheumatoid arthritis and other inflammatory conditions. Chronic inflammation of this kind is associated with elevated cardiovascular risk, so it adds another lens on the immune and inflammatory factors that shape heart health.
Included in your annual panel Link
Try a shorter name or another spelling. Looking for something else? Search à la carte tests.
Beyond the annual panel
Follow-up tests are à la carte, at our lab cost with no markup. Specialty tests for gut health, nutrition and stress are coming to the app.